The source is also providing more information like the publication year, authors and more. Product safety assessment dow methyl isobutyl ketone. Acetone is a commonly used material in the manufacture of various chemicals like methyl isobutyl ketone, mesityl oxide, diacetone alcohol, acetic acid via the ketene process, iodoform, and bromoform. This structure is also available as a 2d mol file or as a computed 3d sd file the 3d structure may be viewed using java or javascript. Common synonyms for methyl isobutyl ketone mibk include 4 methyl 2pentanone, 2 methyl 4pentanone, 4 methyl pentan2one, 2 methyl propyl methyl ketone, isopropyl acetone, isobutyl methyl ketone, 4 methyl 2oxopentane, hexone, and hexanone hsdb, 2000. Safety assessment of mibk methyl isobutyl ketone1 sage journals. Pdf study of the interaction of polymethylmethacrylate fragments. Exposure to methyl isobutyl ketone during spray painting was found to be 0. Methyl isobutyl ketone mibk is an organic compound. Pdf 23 pp, 162 k not assessed under the iris program. Firstly acetone undergoes an aldol condensation diacetone alcohol, which readily dehydrates to give. P210 keep away from heat, sparks, open flames or hot surfaces. It can also be used as a raw material in a chemical synthesis. Methyl isobutyl ketone is also used in uranium extraction.
N methyln nitronnitrosoguanidine mnng served as the positive control. Nov 16, 2016 organic chemistry the aliphatic ketone ch32chch2coch3, that is used as a solvent. Methyl isobutyl ketone national pollutant inventory. Gas 7 mmhg, n2 added, total pressure 600 mmhg instrument. Ethyl isobutyl ketone is occasionally found as a volatile component of normal human biofluids. Some of the industries that use it in production are chemical industry, rubber manufacturers, pharmaceutical industry, the semiconductor industry, manufacturers of millwork, veneer and plywood and the manufacturers of paints, varnishes and lacquers. Toxicity and carcinogenicity of methyl isobutyl ketone in. Methyl isobutyl ketone mibk is primarily used as a denaturant for rubbing alcohol, as a solvent and in the manufacture of methyl amyl alcohol. Methyl isobutyl ketone mibk is the organic compound with the formula ch32chch2coch3. More than 60% of methyl isobutyl ketone is produced by aldol condensation of acetone and its derivative intermediates, diacetone alcohol and mesityl oxide. Inhalation of vapors is the most likely route of exposure in the work place. Safety data sheet according to whs and adg requirements. Methyl isobutyl ketone can affect you when breathed in.
Methyl isobutyl ketone is incompatible with caustic soda and other strong alkalis, hydrochloric acid, sulfuric acid and other strong inorganic acids, amines and oxidizing agents such as hydrogen peroxide, nitric acid, perchloric acid and chromium trioxide. Some relevant physical and chemical properties of mibk are shown in table 21. E1 specification for astm liquidinglass thermometers. Astm d1153 12 standard specification for methyl isobutyl ketone. Methyl isobutyl ketone is a solvent used in coatings and adhesives. Sales specification 1 of 1 methyl isobutyl ketone specifications1 units limits methyl isobutyl ketone wt.
Pdf exposure of polymethylmethacrylate pmma during electron beamlithography ebl produces. Methyl isobutyl ketone peroxide cameo chemicals noaa. Methyl isobutyl ketone mibk market size, 2018 industry. Onestep methyl isobutyl ketone synthesis from acetone and. When the target gas or substance is unknown our specialty hazmat kits provide an excellent answer for quick identification and measurement. Containers, even those that have been emptied, can contain explosive vapours. D4052 test method for density, relative density, and api gravity of liquids by digital density meter. Photograph your local culture, help wikipedia and win. Methyl isobutyl ketone c6h12o chemical abstracts service cas number.
This colourless liquid, a ketone, is widely used as a solvent. Breathing methyl isobutyl ketone can irritate the nose and throat causing coughing and wheezing. Water solubility is not good compare to other ketone solvents like acetone and mek methyl ethyl ketone. More information on the manner in which spectra in this collection were collected can be found here.
Methyl isobutyl ketone is also used as a solvent in paint and lacquers. Methyl isobutyl ketone mibk is the organic compound with the formula ch 3 2 chch 2 c och 3. Year average result samples taken detections range of results. Spegcftd determination of nmethyl2pyrrolidone and its metabolites in urine.
D3329 test method for purity of methyl isobutyl ketone by gas chromatography. Do not cut, drill, grind, weld or perform similar operations on or near. Toxicological profile for 2hexanone agency for toxic substances. It is a stable, clear, and colorless liquid with a pleasant odor. Mibk can also be used in order to extract, separate and purify various products. Strongly reduced material such as sulfides, nitrides, and hydrides may react explosively with peroxides. Methyl isobutyl ketone mibk is also known as mono isobutyl ketone. It is used in the pharmaceutical, agrochemical industries, in fine chemistry. Methyl isobutyl ketone petition toxics release inventory. Common synonyms for methyl isobutyl ketone mibk include 4methyl2pentanone, 2methyl4pentanone, 4methyl pentan2one, 2methyl propyl methyl ketone, isopropyl acetone, isobutyl methyl ketone, 4methyl2oxopentane, hexone, and hexanone hsdb, 2000. Methyl isobutyl ketone occupational exposure survey niosh, 1990 conducted from 1981 to 1983, the number of workers potentially exposed to methyl isobutyl ketone in the usa was estimated as 48 000. Please see second page physical properties molecular weight 100. A wide variety of methyl isobutyl ketone options are available to you, such as grade standard.
Sensory irritation and pulmonary irritation of nmethyl ketones. Preparation of methyl isobutyl ketone download pdf. It is used in the semiconductor industry and the fragrance and flavor industry. Except where noted, spectra from this collection were measured on dispersive instruments, often in carefully selected solvents, and hence may differ in detail from measurements on ftir instruments or in other chemical environments. It is both a mediumboiling and a mediumevaporating solvent.
This structure is also available as a 2d mol file or as a computed 3d sd file. Methyl isobutyl ketone mibk is a clear liquid with a mild characteristic odor. Sigmaaldrich offers a number of methyl isobutyl ketone products. Reference dose for oral exposure rfd pdf 23 pp, 162 k last updated. Methyl isobutyl ketone product specification version 8a specifications minimum maximum test method purity wt% wet basis 99. Isobutyl methyl ketone c 6, isopropylacetone c 6, mibk c 6, methyl isobutyl ketone c 6 linear formula.
Methyl isobutyl ketone article about methyl isobutyl. This iris assessment for methyl isobutyl ketone mibk consists of hazard identification and doseresponse assessment data and provides support for epa risk management decisions. The methyl isobutyl ketone 5300 ppm gas detector tube system is perfect when sampling for methyl isobutyl ketone or literally hundreds of other gases. Methyl isobutyl ketone market size, share, emerging trend. Other products where acetone is utilized in manufacture include rayon, photographic films, and. Reports emphasize developments for acetone, methyl ethyl ketone and methyl isobutyl ketone that have potential implications for the chemical and energy industries customer logins obtain the data you need to make the most informed decisions by accessing our extensive portfolio of information, analytics, and expertise. Methyl isobutyl ketone request for relevant information on chemical being considered for listing by the authoritative bodies mechanism. Methyl isobutyl ketone mibk is also produced during conversion of isopropanol.
Breathing the vapor can cause headache, loss of appetite, nausea, vomiting, and diarrhea. Methyl isobutyl ketone mibk casrn 108101 iris us epa, ord. Mibk is a solvent used in manufacturing paints, rubbers, pharmaceuticals, other chemicals, usually in the semiconductor, fragrance, and flavor industries. Methyl isobutyl ketone is made from acetone via a threestep process. Methyl isobutyl ketone is an aggressive, polar solvent with a moderate evaporation rate. D5386 test method for color of liquids using tristimulus colorimetry. Methyl isobutyl ketone mibk revision date 03212019 version 4. Methyl isobutyl ketone is manufactured from acetone via a threestep process. Methyl isobutyl ketone 5300 ppm gas detector tube sensidyne. Methyl isobutyl ketone is made from acetone via a threestep.
Methyl isobutyl ketone occurs as a colorless, flammable liquid that is moderately soluble in water. Mibk methylisobutylketone is a stable, medium evaporating liquid and compatible with many organic materials, which makes it a good industrial solvent. Mibkis also known as hexone, isobutyl methyl ketone, and isohexanone. There are few chemical classes that do not at least produce heat when mixed with peroxides. Explore information about air pollutants, contaminants and studies being done. Mibk methylisobutylketone has a medium evaporation rate and is miscible in many organic solvent. Epa has denied a petition to remove methyl isobutyl ketone mibk from the list of chemicals subject to the reporting requirements under section 3 of the emergency planning and community righttoknow act epcra and section 6607 of the pollution prevention act ppa. Mibk methyl isobutyl ketone is an aliphatic ketone that func tions as both a. The american conference of governmental industrial hygienists acgih threshold limit valuetimeweighted average tlvtwa and tlvshort term exposure limit tlvstel for mibk are 50 and 75 ppm, respectively. Find more compounds similar to methyl isobutyl ketone note. Peroxides, such as methyl isobutyl ketone peroxide, are good oxidizing agents. Mibk is wildly used in fine chemistry, rubber industry or in coating industry. Showing metabocard for methyl isobutyl ketone hmdb0002939. Methyl isobutyl ketone mibk 4methyl2pentanone cas no.
P261 avoid breathing dust, fume, gas, mist, vapours, spray. This compound has particular features such as it is clear, colorless, has pleasant odor, is very flammable with high vapor pressure, and can be widely utilized as a solvent. It is a component of the feces in about 25% of the normal population. Volatile organic compounds from feces have the potential to help in the diagnosis of gastrointestinal disease. Reference concentration for inhalation exposure rfc pdf 23 pp, 162 k last updated.
Diffusive used to give an ethereal quality to fragrances, add lift and is particularly useful where a fruity element is desired, where it can enhance the top note, giving a more juicy effect. Hazards identification continued precautionary statements prevention. Methyl isobutyl ketone is used as a solvent for manufacturing. Methyl isobutyl ketone is a dairy, fruity, and green tasting compound. The primary sources of methyl isobutyl ketone are the industries that manufacture it or use it in production. Ntizestwpvyfnl uhfffaoysan methyl isobutyl ketone chemical compound data. Methyl isobutyl ketone some chemicals present in industrial. Methyl isobutyl ketone material safety data sheet 1. Acetone methyl ethyl ketone mek and methyl isobutyl ketone.
Methyl isobutyl ketone mibk is a solvent used in numerous products and processes and may be present in the air of the workplace as a vapor. Chemical properties of methyl isobutyl ketone cas 108101. When the target gas or substance is unknown our specialty hazmat kits provide an excellent answer for. P243 take precautionary measures against static discharge. Methyl isobutyl ketone is utilized as a solvent for manufacturing pharmaceuticals, paints, rubber, chemicals, etc. If breathing is irregular or stopped, administer artificial respiration. Methyl isobutyl ketone mibk, hexanone 2pentanone, 4methyl 4methyl2pentanone ch3coch2chch32 description mibk is a stable, colorless liquid with a pleasant odor. Around 60% of the mibk is manufactured by aldol condensation of acetone and its derivative intermediates, mesityl oxide, and diacetone alcohol.
Methyl isobutyl ketone mibk is the organic compound with the formula ch 3 2 chch 2 coch 3. Back to top product uses7,8 methyl isobutyl ketone is primarily used in solvent applications for the following. Organic compounds can ignite on contact with concentrated peroxides. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. One of the most useful among the acetone derivate solvents, it. Methyl isobutyl ketone 2012 priority list for the development of proposition 65 nsrls for carcinogens and madls for chemicals causing reproductive toxicity. Methyl isobutyl ketone is also considered to be an excellent solvent for resins used in the production of surface coating and is widely used in rubber chemicals for the production of tyres. Methyl isobutyl ketone c6h12o chemical abstracts service. Chemeo is only indexing the data, follow the source links to retrieve the latest data. Mibk is used as solvent for paints and resinbased protective coating systems 23,24 and is a reagent for. Methyl isobutyl ketone pdhg mibk nov2011 page 1 of 6 methyl isobutyl ketone mibk 4methyl2pentanone cas no. This colourless liquid, a ketone, is used as a solvent for gums, resins, paints, varnishes, lacquers, and nitrocellulose.
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